Rocksmith System Requirements:
Minimum System requirements for Rocksmith is yet unknown, however you can check the recommended requirements below. It seems like Rocksmith wont need any high end pc config. You can emjoy the game on standard gaming PC as well.
Recommended System Requirements:
Operating System: Windows XP
CPU: Intel Pentium D 830 3.0GHz / Sempron 140
Video Card: Nvidia GeForce 7800 GT / AMD Radeon X800 XT
Memory: 2GB RAM
HDD Space : 1GB
Direct X: DX 9
Rocksmith is releasing on October 16th 2012.